Development of Hydroxamic Acid Compounds for Inhibition of Metallo-β-Lactamase from Bacillus anthracis

The emergence of resistant bacteria takes place, endangering the effectiveness of antibiotics. A reason for antibiotic resistance is the presence of lactamases that catalyze the hydrolysis of β-lactam antibiotics. An inhibitor of serine-β-lactamases such as clavulanic acid binds to the active site o...

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Detalles Bibliográficos
Autores principales: Huckleby, Andrew E., Saul, Jhawn G., Shin, Hyunshun, Desmarais, Staci, Bokka, Apparao, Jeon, Junha, Kim, Sung-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408887/
https://www.ncbi.nlm.nih.gov/pubmed/36012433
http://dx.doi.org/10.3390/ijms23169163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408887/
https://www.ncbi.nlm.nih.gov/pubmed/36012433
http://dx.doi.org/10.3390/ijms23169163

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