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Development of Hydroxamic Acid Compounds for Inhibition of Metallo-β-Lactamase from Bacillus anthracis
The emergence of resistant bacteria takes place, endangering the effectiveness of antibiotics. A reason for antibiotic resistance is the presence of lactamases that catalyze the hydrolysis of β-lactam antibiotics. An inhibitor of serine-β-lactamases such as clavulanic acid binds to the active site o...
Autores principales: | Huckleby, Andrew E., Saul, Jhawn G., Shin, Hyunshun, Desmarais, Staci, Bokka, Apparao, Jeon, Junha, Kim, Sung-Kun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408887/ https://www.ncbi.nlm.nih.gov/pubmed/36012433 http://dx.doi.org/10.3390/ijms23169163 |
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