CDNF Interacts with ER Chaperones and Requires UPR Sensors to Promote Neuronal Survival

Cerebral dopamine neurotrophic factor (CDNF) is a neurotrophic factor that has beneficial effects on dopamine neurons in both in vitro and in vivo models of Parkinson’s disease (PD). CDNF was recently tested in phase I-II clinical trials for the treatment of PD, but the mechanisms underlying its neu...

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Detalles Bibliográficos
Autores principales: Eesmaa, Ave, Yu, Li-Ying, Göös, Helka, Danilova, Tatiana, Nõges, Kristofer, Pakarinen, Emmi, Varjosalo, Markku, Lindahl, Maria, Lindholm, Päivi, Saarma, Mart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408947/
https://www.ncbi.nlm.nih.gov/pubmed/36012764
http://dx.doi.org/10.3390/ijms23169489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408947/
https://www.ncbi.nlm.nih.gov/pubmed/36012764
http://dx.doi.org/10.3390/ijms23169489

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