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Dynamic Alteration Profile and New Role of RNA m6A Methylation in Replicative and H(2)O(2)-Induced Premature Senescence of Human Embryonic Lung Fibroblasts

N6-methyladenosine (m6A) methylation is one of the most common RNA modifications, regulating RNA fate at the posttranscriptional level, and is closely related to cellular senescence. Both models of replicative and premature senescence induced by hydrogen peroxide (H(2)O(2)) were used to detect m6A r...

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Detalles Bibliográficos
Autores principales: Wu, Fan, Zhang, Luyun, Lai, Caiyun, Peng, Xinyue, Yu, Susu, Zhou, Cheng, Zhang, Bo, Zhang, Wenjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408987/
https://www.ncbi.nlm.nih.gov/pubmed/36012545
http://dx.doi.org/10.3390/ijms23169271