Cargando…

Dynamic Alteration Profile and New Role of RNA m6A Methylation in Replicative and H(2)O(2)-Induced Premature Senescence of Human Embryonic Lung Fibroblasts

N6-methyladenosine (m6A) methylation is one of the most common RNA modifications, regulating RNA fate at the posttranscriptional level, and is closely related to cellular senescence. Both models of replicative and premature senescence induced by hydrogen peroxide (H(2)O(2)) were used to detect m6A r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Fan, Zhang, Luyun, Lai, Caiyun, Peng, Xinyue, Yu, Susu, Zhou, Cheng, Zhang, Bo, Zhang, Wenjuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408987/ https://www.ncbi.nlm.nih.gov/pubmed/36012545 http://dx.doi.org/10.3390/ijms23169271

Ejemplares similares

Down-Regulation of Fibroblast Growth Factor 2 (FGF2) Contributes to the Premature Senescence of Mouse Embryonic Fibroblast
por: Li, Jie, et al.
Publicado: (2020)

Novel Roles of RNA m6A Methylation Regulators in the Occurrence of Alzheimer’s Disease and the Subtype Classification
por: Li, Min, et al.
Publicado: (2022)

Effect of antioxidants on the H(2)O(2)-induced premature senescence of human fibroblasts
por: Pieńkowska, Natalia, et al.
Publicado: (2020)

New roles of N6-methyladenosine methylation system regulating the occurrence of non-alcoholic fatty liver disease with N6-methyladenosine-modified MYC
por: Cheng, Wenli, et al.
Publicado: (2022)

Downregulation of IGFBP5 contributes to replicative senescence via ERK2 activation in mouse embryonic fibroblasts
por: Nojima, Iyori, et al.
Publicado: (2022)

Conditioned medium derived from human amniotic stem cells delays H(2)O(2)-induced premature senescence in human dermal fibroblasts
por: Pan, Changwei, et al.
Publicado: (2019)

SORBS2 and TLR3 induce premature senescence in primary human fibroblasts and keratinocytes
por: Liesenfeld, Melanie, et al.
Publicado: (2013)

CBX4 Regulates Replicative Senescence of WI-38 Fibroblasts
por: Chen, Yu-Hsiu, et al.
Publicado: (2022)

Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts
por: Kang, Hyun Tae, et al.
Publicado: (2011)

Senescent macrophages alter fibroblast fibrogenesis in response to SARS-CoV-2 infection
por: Pence, Brandt, et al.
Publicado: (2022)

Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence
por: Kural, Kamil C., et al.
Publicado: (2016)

Premature senescence of cardiac fibroblasts and atrial fibrosis in patients with atrial fibrillation
por: Xie, Jun, et al.
Publicado: (2017)

Rice Premature Leaf Senescence 2, Encoding a Glycosyltransferase (GT), Is Involved in Leaf Senescence
por: Wang, Min, et al.
Publicado: (2018)

Tuberculosis infection and epidemiological characteristics in Haidian District, Beijing, 2005–2018
por: Wu, Fan, et al.
Publicado: (2020)

Elimination of protein aggregates prevents premature senescence in human trisomy 21 fibroblasts
por: Nawa, Nobutoshi, et al.
Publicado: (2019)

Bisdemethoxycurcumin Increases Sirt1 to Antagonize t-BHP-Induced Premature Senescence in WI38 Fibroblast Cells
por: Li, Ying-Bo, et al.
Publicado: (2013)

Replicatively senescent human fibroblasts reveal a distinct intracellular metabolic profile with alterations in NAD+ and nicotinamide metabolism
por: James, Emma L., et al.
Publicado: (2016)

A potential role for NEDD1 and the centrosome in senescence of mouse embryonic fibroblasts
por: Manning, J A, et al.
Publicado: (2010)

Antiviral Effect of Lithium Chloride on Replication of Marek’s Disease Virus in Chicken Embryonic Fibroblasts
por: He, Huifeng, et al.
Publicado: (2021)

Epigallocatechin gallate prevents senescence by alleviating oxidative stress and inflammation in WI-38 human embryonic fibroblasts
por: Zhang, Qiao, et al.
Publicado: (2019)

Piper betle L. Modulates Senescence-Associated Genes Expression in Replicative Senescent Human Diploid Fibroblasts
por: Durani, Lina Wati, et al.
Publicado: (2017)

Regulation of Cr(VI)-Induced Premature Senescence in L02 Hepatocytes by ROS-Ca(2+)-NF-κB Signaling
por: Zhang, Yujing, et al.
Publicado: (2022)

BRE plays an essential role in preventing replicative and DNA damage-induced premature senescence
por: Shi, Wenting, et al.
Publicado: (2016)

Epigenetic modulation upon exposure of lung fibroblasts to TiO(2) and ZnO nanoparticles: alterations in DNA methylation
por: Patil, Nayana A, et al.
Publicado: (2016)

Transcriptome divergence between developmental senescence and premature senescence in Nicotiana tabacum L.
por: Zhao, Zhe, et al.
Publicado: (2020)

A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta
por: Bielak-Zmijewska, Anna, et al.
Publicado: (2013)

Malvidin Protects WI-38 Human Fibroblast Cells Against Stress-induced Premature Senescence
por: Seo, Hye Rin, et al.
Publicado: (2016)

Senescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotype
por: Del Rey, Manuel J., et al.
Publicado: (2019)

Altered myogenesis and premature senescence underlie human TRIM32-related myopathy
por: Servián-Morilla, E., et al.
Publicado: (2019)

Heat Shock Alters Mesenchymal Stem Cell Identity and Induces Premature Senescence
por: Shimoni, Chen, et al.
Publicado: (2020)

Preventive Effects of Epigallocatechin-3-O-Gallate against Replicative Senescence Associated with p53 Acetylation in Human Dermal Fibroblasts
por: Han, Dong-Wook, et al.
Publicado: (2012)

Effect of theaflavin-3,3′-digallate on leptin-deficient induced nonalcoholic fatty liver disease might be related to lipid metabolism regulated by the Fads1/PPARδ/Fabp4 axis and gut microbiota
por: Zhou, Cheng, et al.
Publicado: (2022)

Asxl1 deficiency in embryonic fibroblasts leads to cellular senescence via impairment of the AKT-E2F pathway and Ezh2 inactivation
por: Youn, Hye Sook, et al.
Publicado: (2017)

Role of p16(INK4A) in Replicative Senescence and DNA Damage-Induced Premature Senescence in p53-Deficient Human Cells
por: Mirzayans, Razmik, et al.
Publicado: (2012)

Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing
por: Burton, Dominick G. A., et al.
Publicado: (2018)

Identification of the lncRNA, AK156230, as a novel regulator of cellular senescence in mouse embryonic fibroblasts
por: Chen, Yu-ning, et al.
Publicado: (2016)

Premature senescence of the liver in Alagille patients
por: Jannone, Giulia, et al.
Publicado: (2023)

SOX19b regulates the premature neuronal differentiation of neural stem cells through EZH2-mediated histone methylation in neural tube development of zebrafish
por: Li, Xian, et al.
Publicado: (2019)

E2F1 mediates the downregulation of POLD1 in replicative senescence
por: Gao, Shichao, et al.
Publicado: (2019)

Senescence-activated enhancer landscape orchestrates the senescence-associated secretory phenotype in murine fibroblasts
por: Guan, Yiting, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rj2r7oe6vjlp767v7p6quciq09