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Mass Spectrometric Metabolic Fingerprinting of 2-Deoxy-D-Glucose (2-DG)-Induced Inhibition of Glycolysis and Comparative Analysis of Methionine Restriction versus Glucose Restriction under Perfusion Culture in the Murine L929 Model System

All forms of restriction, from caloric to amino acid to glucose restriction, have been established in recent years as therapeutic options for various diseases, including cancer. However, usually there is no direct comparison between the different restriction forms. Additionally, many cell culture ex...

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Detalles Bibliográficos
Autores principales: Volland, Julian Manuel, Kaupp, Johannes, Schmitz, Werner, Wünsch, Anna Chiara, Balint, Julia, Möllmann, Marc, El-Mesery, Mohamed, Frackmann, Kyra, Peter, Leslie, Hartmann, Stefan, Kübler, Alexander Christian, Seher, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408990/
https://www.ncbi.nlm.nih.gov/pubmed/36012485
http://dx.doi.org/10.3390/ijms23169220