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Effects of Polymers on the Drug Solubility and Dissolution Enhancement of Poorly Water-Soluble Rivaroxaban

The purpose of this study was to investigate the efficacy of hydrophilic polymers in a solid dispersion formulation in improving the solubility and dissolution rate of rivaroxaban (RXB), a poorly soluble drug. The developed solid dispersion consisted of two components, a drug and a polymer, and the...

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Detalles Bibliográficos
Autores principales: Choi, Min-Jong, Woo, Mi Ran, Choi, Han-Gon, Jin, Sung Giu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409000/
https://www.ncbi.nlm.nih.gov/pubmed/36012748
http://dx.doi.org/10.3390/ijms23169491