Dietary Cholic Acid Exacerbates Liver Fibrosis in NASH Model of Sprague–Dawley Rats Fed a High-Fat and High-Cholesterol Diet

Background: Recently, we established a novel rodent model of nonalcoholic steatohepatitis (NASH) with advanced fibrosis induced by a high-fat and high-cholesterol (HFC) diet containing cholic acid (CA), which is known to cause hepatotoxicity. The present study aimed to elucidate the direct impact of...

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Detalles Bibliográficos
Autores principales: Ichimura-Shimizu, Mayuko, Watanabe, Shiro, Kashirajima, Yuka, Nagatomo, Ami, Wada, Hitomi, Tsuneyama, Koichi, Omagari, Katsuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409005/
https://www.ncbi.nlm.nih.gov/pubmed/36012527
http://dx.doi.org/10.3390/ijms23169268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409005/
https://www.ncbi.nlm.nih.gov/pubmed/36012527
http://dx.doi.org/10.3390/ijms23169268

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