Molecular Events behind the Selectivity and Inactivation Properties of Model NaK-Derived Ion Channels

Y55W mutants of non-selective NaK and partly K(+)-selective NaK2K channels have been used to explore the conformational dynamics at the pore region of these channels as they interact with either Na(+) or K(+). A major conclusion is that these channels exhibit a remarkable pore conformational flexibi...

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Detalles Bibliográficos
Autores principales: Giudici, Ana Marcela, Renart, María Lourdes, Coutinho, Ana, Morales, Andrés, González-Ros, José Manuel, Poveda, José Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409022/
https://www.ncbi.nlm.nih.gov/pubmed/36012519
http://dx.doi.org/10.3390/ijms23169246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409022/
https://www.ncbi.nlm.nih.gov/pubmed/36012519
http://dx.doi.org/10.3390/ijms23169246

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