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Molecular Events behind the Selectivity and Inactivation Properties of Model NaK-Derived Ion Channels
Y55W mutants of non-selective NaK and partly K(+)-selective NaK2K channels have been used to explore the conformational dynamics at the pore region of these channels as they interact with either Na(+) or K(+). A major conclusion is that these channels exhibit a remarkable pore conformational flexibi...
Autores principales: | Giudici, Ana Marcela, Renart, María Lourdes, Coutinho, Ana, Morales, Andrés, González-Ros, José Manuel, Poveda, José Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409022/ https://www.ncbi.nlm.nih.gov/pubmed/36012519 http://dx.doi.org/10.3390/ijms23169246 |
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