Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas

It is emerging that targeting the adaptive functions of Unfolded Protein Response (UPR) may represent a promising anti-cancer therapeutic approach. This is particularly relevant for B-cell lymphomas, characterized by a high level of constitutive stress due to high c-Myc expression. In this study, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Benedetti, Rossella, Arena, Andrea, Romeo, Maria Anele, Gilardini Montani, Maria Saveria, Gonnella, Roberta, Santarelli, Roberta, Trivedi, Pankaj, Cirone, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409055/
https://www.ncbi.nlm.nih.gov/pubmed/36012375
http://dx.doi.org/10.3390/ijms23169113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409055/
https://www.ncbi.nlm.nih.gov/pubmed/36012375
http://dx.doi.org/10.3390/ijms23169113

Ejemplares similares