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Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas

It is emerging that targeting the adaptive functions of Unfolded Protein Response (UPR) may represent a promising anti-cancer therapeutic approach. This is particularly relevant for B-cell lymphomas, characterized by a high level of constitutive stress due to high c-Myc expression. In this study, we...

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Detalles Bibliográficos
Autores principales:	Benedetti, Rossella, Arena, Andrea, Romeo, Maria Anele, Gilardini Montani, Maria Saveria, Gonnella, Roberta, Santarelli, Roberta, Trivedi, Pankaj, Cirone, Mara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409055/ https://www.ncbi.nlm.nih.gov/pubmed/36012375 http://dx.doi.org/10.3390/ijms23169113

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