Stabilization of the c-Myc Protein via the Modulation of Threonine 58 and Serine 62 Phosphorylation by the Disulfiram/Copper Complex in Oral Cancer Cells

MYC has a short half-life that is tightly regulated through phosphorylation and proteasomal degradation. Many studies have claimed that treatment with disulfiram (DSF) with or without copper ions can cause cancer cell death in a reactive oxygen species (ROS)-dependent manner in cancer cells. Our pre...

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Detalles Bibliográficos
Autores principales: Chen, Gunng-Shinng, Chen, Ssu-Yu, Liu, Shu-Ting, Hsieh, Cheng-Chih, Lee, Shiao-Pieng, Huang, Shih-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409128/
https://www.ncbi.nlm.nih.gov/pubmed/36012403
http://dx.doi.org/10.3390/ijms23169137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409128/
https://www.ncbi.nlm.nih.gov/pubmed/36012403
http://dx.doi.org/10.3390/ijms23169137

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