Kinetic Characterization of Cerium and Gallium Ions as Inhibitors of Cysteine Cathepsins L, K, and S

Heavy metal ions can disrupt biological functions via multiple molecular mechanisms, including inhibition of enzymes. We investigate the interactions of human papain-like cysteine endopeptidases cathepsins L, K, and S with gallium and cerium ions, which are associated with medical applications. We c...

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Detalles Bibliográficos
Autores principales: Novinec, Marko, Bembič, Primož, Janković, Milica, Kisilak, Marija, Kljun, Jakob, Turel, Iztok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409168/
https://www.ncbi.nlm.nih.gov/pubmed/36012257
http://dx.doi.org/10.3390/ijms23168993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409168/
https://www.ncbi.nlm.nih.gov/pubmed/36012257
http://dx.doi.org/10.3390/ijms23168993

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