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Increased Gene Targeting in Hyper-Recombinogenic LymphoBlastoid Cell Lines Leaves Unchanged DSB Processing by Homologous Recombination

In the cells of higher eukaryotes, sophisticated mechanisms have evolved to repair DNA double-strand breaks (DSBs). Classical nonhomologous end joining (c-NHEJ), homologous recombination (HR), alternative end joining (alt-EJ) and single-strand annealing (SSA) exploit distinct principles to repair DS...

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Detalles Bibliográficos
Autores principales: Mladenov, Emil, Paul-Konietzko, Katja, Mladenova, Veronika, Stuschke, Martin, Iliakis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409177/
https://www.ncbi.nlm.nih.gov/pubmed/36012445
http://dx.doi.org/10.3390/ijms23169180