Targeting ABCC6 in Mesenchymal Stem Cells: Impairment of Mature Adipocyte Lipid Homeostasis

Mutations in ABCC6, an ATP-binding cassette transporter with a so far unknown substrate mainly expressed in the liver and kidney, cause pseudoxanthoma elasticum (PXE). Symptoms of PXE in patients originate from the calcification of elastic fibers in the skin, eye, and vessels. Previous studies sugge...

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Detalles Bibliográficos
Autores principales: Plümers, Ricarda, Osterhage, Michel R., Lindenkamp, Christopher, Knabbe, Cornelius, Hendig, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409192/
https://www.ncbi.nlm.nih.gov/pubmed/36012482
http://dx.doi.org/10.3390/ijms23169218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409192/
https://www.ncbi.nlm.nih.gov/pubmed/36012482
http://dx.doi.org/10.3390/ijms23169218

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