Cargando…

The Catalytic Subunit of Schizosaccharomyces pombe CK2 (Cka1) Negatively Regulates RNA Polymerase II Transcription through Phosphorylation of Positive Cofactor 4 (PC4)

Positive cofactor 4 (PC4) is a transcriptional coactivator that plays important roles in transcription and DNA replication. In mammals, PC4 is phosphorylated by CK2, and this event downregulates its RNA polymerase II (RNAPII) coactivator function. This work describes the effect of fission yeast PC4...

Descripción completa

Detalles Bibliográficos
Autores principales: Rojas, Diego A., Urbina, Fabiola, Solari, Aldo, Maldonado, Edio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409219/
https://www.ncbi.nlm.nih.gov/pubmed/36012759
http://dx.doi.org/10.3390/ijms23169499