Alpha-Ketoglutarate or 5-HMF: Single Compounds Effectively Eliminate Leukemia Cells via Caspase-3 Apoptosis and Antioxidative Pathways

Background: We recently showed that a combined solution containing alpha-ketoglutarate (aKG) and 5-hydroxymethyl-furfural (5-HMF) has a solid antitumoral effect on the Jurkat cell line due to the fact of its antioxidative, caspase-3 and apoptosis activities, but no negative effect on human fibroblas...

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Detalles Bibliográficos
Autores principales: Greilberger, Joachim, Herwig, Ralf, Kacar, Mehtap, Brajshori, Naime, Feigl, Georg, Stiegler, Philipp, Wintersteiger, Reinhold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409265/
https://www.ncbi.nlm.nih.gov/pubmed/36012295
http://dx.doi.org/10.3390/ijms23169034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409265/
https://www.ncbi.nlm.nih.gov/pubmed/36012295
http://dx.doi.org/10.3390/ijms23169034

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