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Bisdemethoxycurcumin (BDC)-Loaded H-Ferritin-Nanocages Mediate the Regulation of Inflammation in Alzheimer’s Disease Patients

Background: Bisdemethoxycurcumin (BDC) might be an inflammation inhibitor in Alzheimer’s Disease (AD). However, BDC is almost insoluble in water, poorly absorbed by the organism, and degrades rapidly. We thus developed a new nanoformulation of BDC based on H-Ferritin nanocages (BDC-HFn). Methods: We...

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Detalles Bibliográficos
Autores principales: Gagliardi, Stella, Truffi, Marta, Tinelli, Veronica, Garofalo, Maria, Pandini, Cecilia, Cotta Ramusino, Matteo, Perini, Giulia, Costa, Alfredo, Negri, Sara, Mazzucchelli, Serena, Bonizzi, Arianna, Sitia, Leopoldo, Busacca, Maria, Sevieri, Marta, Mocchi, Michela, Ricciardi, Alessandra, Prosperi, Davide, Corsi, Fabio, Cereda, Cristina, Morasso, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409287/
https://www.ncbi.nlm.nih.gov/pubmed/36012501
http://dx.doi.org/10.3390/ijms23169237