Activation of ADRB2/PKA Signaling Pathway Facilitates Lipid Synthesis in Meibocytes, and Beta-Blocker Glaucoma Drug Impedes PKA-Induced Lipid Synthesis by Inhibiting ADRB2

Meibomian gland dysfunction is one of the main causes of dry eye disease and has limited therapeutic options. In this study, we investigated the biological function of the beta 2-adrenergic receptor (ADRB2)/protein kinase A (PKA) pathway in lipid synthesis and its underlying mechanisms in human meib...

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Detalles Bibliográficos
Autores principales: Jun, Ikhyun, Choi, Young Joon, Kim, Bo-Rahm, Seo, Kyoung Yul, Kim, Tae-im
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409328/
https://www.ncbi.nlm.nih.gov/pubmed/36012741
http://dx.doi.org/10.3390/ijms23169478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409328/
https://www.ncbi.nlm.nih.gov/pubmed/36012741
http://dx.doi.org/10.3390/ijms23169478

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