Effects of G-Quadruplex-Binding Plant Secondary Metabolites on c-MYC Expression

Guanine-rich DNA sequences tending to adopt noncanonical G-quadruplex (G4) structures are over-represented in promoter regions of oncogenes. Ligands recognizing G4 were shown to stabilize these DNA structures and drive their formation regulating expression of corresponding genes. We studied the inte...

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Detalles Bibliográficos
Autores principales: Zenkov, Roman G., Kirsanov, Kirill I., Ogloblina, Anna M., Vlasova, Olga A., Naberezhnov, Denis S., Karpechenko, Natalia Y., Fetisov, Timur I., Lesovaya, Ekaterina A., Belitsky, Gennady A., Dolinnaya, Nina G., Yakubovskaya, Marianna G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409388/
https://www.ncbi.nlm.nih.gov/pubmed/36012470
http://dx.doi.org/10.3390/ijms23169209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409388/
https://www.ncbi.nlm.nih.gov/pubmed/36012470
http://dx.doi.org/10.3390/ijms23169209

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