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Effects of G-Quadruplex-Binding Plant Secondary Metabolites on c-MYC Expression
Guanine-rich DNA sequences tending to adopt noncanonical G-quadruplex (G4) structures are over-represented in promoter regions of oncogenes. Ligands recognizing G4 were shown to stabilize these DNA structures and drive their formation regulating expression of corresponding genes. We studied the inte...
Autores principales: | Zenkov, Roman G., Kirsanov, Kirill I., Ogloblina, Anna M., Vlasova, Olga A., Naberezhnov, Denis S., Karpechenko, Natalia Y., Fetisov, Timur I., Lesovaya, Ekaterina A., Belitsky, Gennady A., Dolinnaya, Nina G., Yakubovskaya, Marianna G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409388/ https://www.ncbi.nlm.nih.gov/pubmed/36012470 http://dx.doi.org/10.3390/ijms23169209 |
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