Mild Therapeutic Hypothermia Protects from Acute and Chronic Renal Ischemia-Reperfusion Injury in Mice by Mitigated Mitochondrial Dysfunction and Modulation of Local and Systemic Inflammation

Renal ischemia-reperfusion (IR) injury can lead to acute kidney injury, increasing the risk of developing chronic kidney disease. We hypothesized that mild therapeutic hypothermia (mTH), 34 °C, applied during ischemia could protect the function and structure of kidneys against IR injuries in mice. I...

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Detalles Bibliográficos
Autores principales: Schleef, Maxime, Gonnot, Fabrice, Pillot, Bruno, Leon, Christelle, Chanon, Stéphanie, Vieille-Marchiset, Aurélie, Rabeyrin, Maud, Bidaux, Gabriel, Guebre-Egziabher, Fitsum, Juillard, Laurent, Baetz, Delphine, Lemoine, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409407/
https://www.ncbi.nlm.nih.gov/pubmed/36012493
http://dx.doi.org/10.3390/ijms23169229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409407/
https://www.ncbi.nlm.nih.gov/pubmed/36012493
http://dx.doi.org/10.3390/ijms23169229

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