β-Galactosylceramidase Deficiency Causes Upregulation of Long Pentraxin-3 in the Central Nervous System of Krabbe Patients and Twitcher Mice

Globoid cell leukodystrophy (GLD), or Krabbe disease, is a neurodegenerative sphingolipidosis caused by genetic deficiency of lysosomal β-galactosylceramidase (GALC), characterized by neuroinflammation and demyelination of the central (CNS) and peripheral nervous system. The acute phase protein long...

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Detalles Bibliográficos
Autores principales: Coltrini, Daniela, Chandran, Adwaid Manu Krishna, Belleri, Mirella, Poliani, Pietro L., Cominelli, Manuela, Pagani, Francesca, Capra, Miriam, Calza, Stefano, Prioni, Simona, Mauri, Laura, Prinetti, Alessandro, Kofler, Julia K., Escolar, Maria L., Presta, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409448/
https://www.ncbi.nlm.nih.gov/pubmed/36012705
http://dx.doi.org/10.3390/ijms23169436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409448/
https://www.ncbi.nlm.nih.gov/pubmed/36012705
http://dx.doi.org/10.3390/ijms23169436

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