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Attenuation of Bone Formation through a Decrease in Osteoblasts in Mutant Mice Lacking the GM2/GD2 Synthase Gene

The ganglioside GD1a has been reported to promote the differentiation of mesenchymal stem cells to osteoblasts in cell culture systems. However, the involvement of gangliosides, including GD1a, in bone formation in vivo remains unknown; therefore, we herein investigated their roles in GM2/GD2 syntha...

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Detalles Bibliográficos
Autores principales: Sasaki, Eri, Hamamura, Kazunori, Mishima, Yoshitaka, Furukawa, Koichi, Nagao, Mayu, Kato, Hanami, Hamajima, Kosuke, Sato, Takuma, Miyazawa, Ken, Goto, Shigemi, Togari, Akifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409452/
https://www.ncbi.nlm.nih.gov/pubmed/36012308
http://dx.doi.org/10.3390/ijms23169044