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Modulation of K(V)4.3-KChIP2 Channels by IQM-266: Role of DPP6 and KCNE2

The transient outward potassium current (I(tof)) is generated by the activation of K(V)4 channels assembled with KChIP2 and other accessory subunits (DPP6 and KCNE2). To test the hypothesis that these subunits modify the channel pharmacology, we analyzed the electrophysiological effects of (3-(2-(3-...

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Detalles Bibliográficos
Autores principales: de Benito-Bueno, Angela, Socuellamos, Paula G., Merinero, Yaiza G., Cercos, Pilar, Izquierdo, Carolina, Daniel-Mozo, Miguel, Marín-Olivero, Irene, Perez-Lara, Angel, Gonzalez-Vera, Juan A., Orte, Angel, Albert, Armando, Martin-Martinez, Mercedes, Gutierrez-Rodriguez, Marta, Valenzuela, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409462/
https://www.ncbi.nlm.nih.gov/pubmed/36012438
http://dx.doi.org/10.3390/ijms23169170