ADAR1 Isoforms Regulate Let-7d Processing in Idiopathic Pulmonary Fibrosis

Double-stranded RNA adenosine deaminase 1 (ADAR1) is significantly down-regulated in fibroblasts derived from Idiopathic Pulmonary Fibrosis (IPF) patients, and its overexpression restored levels of miRNA-21, PELI1, and SPRY2. There are two ADAR1 isoforms in humans, ADAR1-p110 and ADAR1-p150, generat...

Descripción completa

Detalles Bibliográficos
Autores principales: Díaz-Piña, Gabriela, Rubio, Karla, Ordoñez-Razo, Rosa M., Barreto, Guillermo, Montes, Eduardo, Becerril, Carina, Salgado, Alfonso, Cabrera-Fuentes, Héctor, Aquino-Galvez, Arnoldo, Carlos-Reyes, Angeles, Ruiz, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409484/
https://www.ncbi.nlm.nih.gov/pubmed/36012303
http://dx.doi.org/10.3390/ijms23169028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409484/
https://www.ncbi.nlm.nih.gov/pubmed/36012303
http://dx.doi.org/10.3390/ijms23169028

Ejemplares similares