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Universal protection against influenza viruses by multi-subtype neuraminidase and M2 ectodomain virus-like particle

Annual influenza vaccination is recommended to update the variable hemagglutinin antigens. Here, we first designed a virus-like particle (VLP) displaying consensus multi-neuraminidase (NA) subtypes (cN1, cN2, B cNA) and M2 ectodomain (M2e) tandem repeat (m-cNA-M2e VLP). Vaccination of mice with m-cN...

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Detalles Bibliográficos
Autores principales: Kim, Ki-Hye, Li, Zhuo, Bhatnagar, Noopur, Subbiah, Jeeva, Park, Bo Ryoung, Shin, Chong Hyun, Pushko, Peter, Wang, Bao-Zhong, Kang, Sang-Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409530/
https://www.ncbi.nlm.nih.gov/pubmed/36006890
http://dx.doi.org/10.1371/journal.ppat.1010755