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Constructive connectomics: How neuronal axons get from here to there using gene-expression maps derived from their family trees

During brain development, billions of axons must navigate over multiple spatial scales to reach specific neuronal targets, and so build the processing circuits that generate the intelligent behavior of animals. However, the limited information capacity of the zygotic genome puts a strong constraint...

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Detalles Bibliográficos
Autores principales: Kerstjens, Stan, Michel, Gabriela, Douglas, Rodney J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409546/
https://www.ncbi.nlm.nih.gov/pubmed/36006873
http://dx.doi.org/10.1371/journal.pcbi.1010382