Single-Disulfide Conopeptide Czon1107, an Allosteric Antagonist of the Human α3β4 Nicotinic Acetylcholine Receptor

Conopeptides are peptides in the venom of marine cone snails that are used for capturing prey or as a defense against predators. A new cysteine-poor conopeptide, Czon1107, has exhibited non-competitive inhibition with an undefined allosteric mechanism in the human (h) α3β4 nicotinic acetylcholine re...

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Detalles Bibliográficos
Autores principales: Ma, Yuan, Cao, Qiushi, Yang, Mengke, Gao, Yue, Fu, Shuiping, Du, Wenhao, Adams, David J., Jiang, Tao, Tae, Han-Shen, Yu, Rilei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409646/
https://www.ncbi.nlm.nih.gov/pubmed/36005500
http://dx.doi.org/10.3390/md20080497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409646/
https://www.ncbi.nlm.nih.gov/pubmed/36005500
http://dx.doi.org/10.3390/md20080497

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