Studies on Biological and Molecular Effects of Small-Molecule Kinase Inhibitors on Human Glioblastoma Cells and Organotypic Brain Slices

Glioblastoma is the most common and aggressive primary brain tumor. Multiple genetic and epigenetic alterations in several major signaling pathways—including the phosphoinositide 3-kinases (PI3K)/AKT/mTOR and the Raf/MEK/ERK pathway—could be found. We therefore aimed to investigate the biological an...

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Detalles Bibliográficos
Autores principales: Hörnschemeyer, Julia, Kirschstein, Timo, Reichart, Gesine, Sasse, Christin, Venus, Jakob, Einsle, Anne, Porath, Katrin, Linnebacher, Michael, Köhling, Rüdiger, Lange, Falko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409734/
https://www.ncbi.nlm.nih.gov/pubmed/36013437
http://dx.doi.org/10.3390/life12081258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409734/
https://www.ncbi.nlm.nih.gov/pubmed/36013437
http://dx.doi.org/10.3390/life12081258

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