Molecular Pathways in Clonal Hematopoiesis: From the Acquisition of Somatic Mutations to Transformation into Hematologic Neoplasm

Hematopoietic stem cell aging, through the acquisition of somatic mutations, gives rise to clonal hematopoiesis (CH). While a high prevalence of CH has been described in otherwise healthy older adults, CH confers an increased risk of both hematologic and non-hematologic diseases. Classification of C...

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Detalles Bibliográficos
Autores principales: Gaulin, Charles, Kelemen, Katalin, Arana Yi, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410004/
https://www.ncbi.nlm.nih.gov/pubmed/36013314
http://dx.doi.org/10.3390/life12081135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410004/
https://www.ncbi.nlm.nih.gov/pubmed/36013314
http://dx.doi.org/10.3390/life12081135

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