Wnt/β-Catenin-Pathway Alterations and Homologous Recombination Deficiency in Cholangiocarcinoma Cell Lines and Clinical Samples: Towards Specific Vulnerabilities

Cholangiocarcinoma (CCA) features a dismal prognosis with limited treatment options. Genomic studies have unveiled several promising targets in this disease, including fibroblast growth factor receptor (FGFR) fusions and isocitrate dehydrogenase (IDH) mutations. To fully harness the potential of gen...

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Detalles Bibliográficos
Autores principales: Scheiter, Alexander, Hierl, Frederik, Winkel, Ingrid, Keil, Felix, Klier-Richter, Margit, Coulouarn, Cédric, Lüke, Florian, Kandulski, Arne, Evert, Matthias, Dietmaier, Wolfgang, Calvisi, Diego F., Utpatel, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410222/
https://www.ncbi.nlm.nih.gov/pubmed/36013219
http://dx.doi.org/10.3390/jpm12081270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410222/
https://www.ncbi.nlm.nih.gov/pubmed/36013219
http://dx.doi.org/10.3390/jpm12081270

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