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Wnt/β-Catenin-Pathway Alterations and Homologous Recombination Deficiency in Cholangiocarcinoma Cell Lines and Clinical Samples: Towards Specific Vulnerabilities
Cholangiocarcinoma (CCA) features a dismal prognosis with limited treatment options. Genomic studies have unveiled several promising targets in this disease, including fibroblast growth factor receptor (FGFR) fusions and isocitrate dehydrogenase (IDH) mutations. To fully harness the potential of gen...
Autores principales: | Scheiter, Alexander, Hierl, Frederik, Winkel, Ingrid, Keil, Felix, Klier-Richter, Margit, Coulouarn, Cédric, Lüke, Florian, Kandulski, Arne, Evert, Matthias, Dietmaier, Wolfgang, Calvisi, Diego F., Utpatel, Kirsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410222/ https://www.ncbi.nlm.nih.gov/pubmed/36013219 http://dx.doi.org/10.3390/jpm12081270 |
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