Doxycycline Attenuates Doxorubicin-Induced Cardiotoxicity by Improving Myocardial Energy Metabolism in Rats

Aim: Evaluate the influence of doxycycline, an anti-inflammatory and matrix metalloproteinase (MMP) inhibitor, on the attenuation of chronic doxorubicin-induced cardiotoxicity in rats. Methods: We allocated male Wistar rats into four groups: control (C), doxorubicin (D), doxycycline (inhibitor of MM...

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Detalles Bibliográficos
Autores principales: Dantas, Danielle, Pereira, Amanda Gomes, Fujimori, Anderson Seiji Soares, Ribeiro, Ana Paula Dantas, de Almeida Silva, Carol Cristina Vágula, Monte, Marina Gaiato, Corrêa, Camila Renata, Fernandes, Ana Angélica, Bazan, Silmeia Garcia Zanati, Azevedo, Paula Schmidt, Minicucci, Marcos Ferreira, de Paiva, Sergio Alberto Rupp, Zornoff, Leonardo Antônio Mamede, Polegato, Bertha Furlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410319/
https://www.ncbi.nlm.nih.gov/pubmed/36005418
http://dx.doi.org/10.3390/jcdd9080254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410319/
https://www.ncbi.nlm.nih.gov/pubmed/36005418
http://dx.doi.org/10.3390/jcdd9080254

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