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Doxycycline Attenuates Doxorubicin-Induced Cardiotoxicity by Improving Myocardial Energy Metabolism in Rats
Aim: Evaluate the influence of doxycycline, an anti-inflammatory and matrix metalloproteinase (MMP) inhibitor, on the attenuation of chronic doxorubicin-induced cardiotoxicity in rats. Methods: We allocated male Wistar rats into four groups: control (C), doxorubicin (D), doxycycline (inhibitor of MM...
Autores principales: | Dantas, Danielle, Pereira, Amanda Gomes, Fujimori, Anderson Seiji Soares, Ribeiro, Ana Paula Dantas, de Almeida Silva, Carol Cristina Vágula, Monte, Marina Gaiato, Corrêa, Camila Renata, Fernandes, Ana Angélica, Bazan, Silmeia Garcia Zanati, Azevedo, Paula Schmidt, Minicucci, Marcos Ferreira, de Paiva, Sergio Alberto Rupp, Zornoff, Leonardo Antônio Mamede, Polegato, Bertha Furlan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410319/ https://www.ncbi.nlm.nih.gov/pubmed/36005418 http://dx.doi.org/10.3390/jcdd9080254 |
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