Heteronemin and Tetrac Induce Anti-Proliferation by Blocking EGFR-Mediated Signaling in Colorectal Cancer Cells

Overexpressed EGFR and mutant K-Ras play vital roles in therapeutic resistance in colorectal cancer patients. To search for an effective therapeutic protocol is an urgent task. A secondary metabolite in the sponge Hippospongia sp., Heteronemin, has been shown to induce anti-proliferation in several...

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Detalles Bibliográficos
Autores principales: Unson, Sukanya, Chang, Tung-Cheng, Yang, Yung-Ning, Wang, Shwu-Huey, Huang, Chi-Hung, Crawford, Dana R., Huang, Haw-Ming, Li, Zi-Lin, Lin, Hung-Yun, Whang-Peng, Jacqueline, Wang, Kuan, Davis, Paul J., Li, Wen-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410344/
https://www.ncbi.nlm.nih.gov/pubmed/36005485
http://dx.doi.org/10.3390/md20080482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410344/
https://www.ncbi.nlm.nih.gov/pubmed/36005485
http://dx.doi.org/10.3390/md20080482

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