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A Novel Marine Pyran-Isoindolone Compound Enhances Fibrin Lysis Mediated by Single-Chain Urokinase-Type Plasminogen Activator

Fungi fibrinolytic compound 1 (FGFC1) is a rare pyran-isoindolone derivative with fibrinolytic activity. The aim of this study was to further determine the effect of FGFC1 on fibrin clots lysis in vitro. We constructed a fibrinolytic system containing single-chain urokinase-type plasminogen activato...

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Detalles Bibliográficos
Autores principales: Gao, Chunli, Tang, Simin, Zhang, Haixing, Zhang, Huishu, Zhang, Tian, Bao, Bin, Zhu, Yuping, Wu, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410493/
https://www.ncbi.nlm.nih.gov/pubmed/36005498
http://dx.doi.org/10.3390/md20080495