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Bps polysaccharide of Bordetella pertussis resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts Escherichia coli into a respiratory pathogen

Infections and disease caused by the obligate human pathogen Bordetella pertussis (Bp) are increasing, despite widespread vaccinations. The current acellular pertussis vaccines remain ineffective against nasopharyngeal colonization, carriage, and transmission. In this work, we tested the hypothesis...

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Detalles Bibliográficos
Autores principales: Fullen, Audra R., Gutierrez-Ferman, Jessica L., Yount, Kacy S., Love, Cheraton F., Choi, Hyun G., Vargas, Mario A., Raju, Deepa, Corps, Kara N., Howell, P. Lynne, Dubey, Purnima, Deora, Rajendar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410548/
https://www.ncbi.nlm.nih.gov/pubmed/35969621
http://dx.doi.org/10.1371/journal.ppat.1010764