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Apoptosis and tissue thinning contribute to symmetric cell division in the developing mouse epidermis in a nonautonomous way

Mitotic spindle orientation (SO) is a conserved mechanism that governs cell fate and tissue morphogenesis. In the developing epidermis, a balance between self-renewing symmetric divisions and differentiative asymmetric divisions is necessary for normal development. While the cellular machinery that...

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Detalles Bibliográficos
Autores principales: Soffer, Arad, Mahly, Adnan, Padmanabhan, Krishnanand, Cohen, Jonathan, Adir, Orit, Loushi, Eidan, Fuchs, Yaron, Williams, Scott E., Luxenburg, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410552/
https://www.ncbi.nlm.nih.gov/pubmed/35969606
http://dx.doi.org/10.1371/journal.pbio.3001756