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EmCyclinD-EmCDK4/6 complex is involved in the host EGF-mediated proliferation of Echinococcus multilocularis germinative cells via the EGFR-ERK pathway

The larval stage of the tapeworm Echinococcus multilocularis causes alveolar echinococcosis (AE), one of the most lethal helminthic infections in humans. The tumor-like growth and development of the metacestode larvae within host organs are driven by a population of somatic stem cells, the germinati...

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Detalles Bibliográficos
Autores principales: Feng, Chonglv, Cheng, Zhe, Xu, Zhijian, Tian, Ye, Tian, Huimin, Liu, Fan, Luo, Damin, Wang, Yanhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410764/
https://www.ncbi.nlm.nih.gov/pubmed/36033888
http://dx.doi.org/10.3389/fmicb.2022.968872