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Multiscale Computer Modeling of Spreading Depolarization in Brain Slices

Spreading depolarization (SD) is a slow-moving wave of neuronal depolarization accompanied by a breakdown of ion concentration homeostasis, followed by long periods of neuronal silence (spreading depression), and is associated with several neurologic conditions. We developed multiscale (ions to tiss...

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Detalles Bibliográficos
Autores principales: Kelley, Craig, Newton, Adam J. H., Hrabetova, Sabina, McDougal, Robert A., Lytton, William W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410770/
https://www.ncbi.nlm.nih.gov/pubmed/35927026
http://dx.doi.org/10.1523/ENEURO.0082-22.2022