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Pigment Epithelium-Derived Factor Protects Retinal Neural Cells and Prevents Pathological Angiogenesis in an Ex Vivo Ischemia Model

Ocular ischemia/hypoxia is a severe problem in ophthalmology that can cause vision impairment and blindness. However, little is known about the changes occurring in the existing fully formed choroidal blood vessels. We developed a new whole organ culture model for ischemia/hypoxia in rat eyes and in...

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Detalles Bibliográficos
Autores principales: Xi, Lei, Tikhonovich, Marina, Biesemeier, Antje, Julien-Schraermeyer, Sylvie, Schraermeyer, Ulrich, Tschulakow, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410835/
https://www.ncbi.nlm.nih.gov/pubmed/36035211
http://dx.doi.org/10.1155/2022/4199394