Melatonin Inhibits the Ferroptosis Pathway in Rat Bone Marrow Mesenchymal Stem Cells by Activating the PI3K/AKT/mTOR Signaling Axis to Attenuate Steroid-Induced Osteoporosis

Steroid-induced osteoporosis (SIOP) is a form of secondary osteoporosis, but its specific mechanism remains unclear. Glucocorticoid (GC-)-induced death of osteoblasts and bone marrow mesenchymal stem cells (BMSCs) is an important factor in SIOP. Ferroptosis is an iron-dependent type of programmed ce...

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Detalles Bibliográficos
Autores principales: Li, Meng, Yang, Ning, Hao, Li, Zhou, Wei, Li, Lei, Liu, Lei, Yang, Fang, Xu, Lei, Yao, Gang, Zhu, Chen, Xu, Wei, Fang, Shiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410838/
https://www.ncbi.nlm.nih.gov/pubmed/36035224
http://dx.doi.org/10.1155/2022/8223737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410838/
https://www.ncbi.nlm.nih.gov/pubmed/36035224
http://dx.doi.org/10.1155/2022/8223737

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