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tRNA-Derived Fragment tRF-5009A Regulates Autophagy and Degeneration of Cartilage in Osteoarthritis via Targeting mTOR

tRNA-derived fragments (tRFs) have been reported to have critical regulatory roles in osteoarthritis (OA). Recent studies have suggested that autophagy promotes the homeostasis of the extracellular matrix of chondrocytes in OA. However, the role of tRFs in posttranscriptional gene regulation during...

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Detalles Bibliográficos
Autores principales: Deng, Zengfa, Long, Dianbo, Liu, Hailong, Xu, Yiyang, Xin, Ruobing, Liao, Hongyi, Li, Zhiwen, Li, Ruiyun, Mao, Guping, Zhang, Ziji, Kang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410839/
https://www.ncbi.nlm.nih.gov/pubmed/36035226
http://dx.doi.org/10.1155/2022/5781660