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Transmissible Endoplasmic Reticulum Stress Mediated by Extracellular Vesicles from Adipocyte Promoting the Senescence of Adipose-Derived Mesenchymal Stem Cells in Hypertrophic Obesity

Hypertrophic obesity, characterized by an excessive expansion of subcutaneous adipocytes, causes chronic inflammation and insulin resistance. It is the primary feature of obesity in middle-aged and elderly individuals. In the adipose microenvironment, a high level of endoplasmic reticulum (ER) stres...

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Detalles Bibliográficos
Autores principales: Fang, Jia, Li, Li, Cao, Xingguo, Yue, Han, Fu, Wanying, Chen, Yi, Xu, Zhiwei, Zhao, Qiongrui, Zhao, Jingge, Wang, Yuebo, Liang, Wulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410860/
https://www.ncbi.nlm.nih.gov/pubmed/36035215
http://dx.doi.org/10.1155/2022/7175027