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BACH2 in TRegs Limits the Number of Adipose Tissue Regulatory T Cells and Restrains Type 2 Immunity to Fungal Allergens

FoxP3+ regulatory T cells (Tregs) are essential for self-tolerance and moderating tissue-damaging inflammation. Tregs that develop and mature in the thymus are classified as central Tregs or effector Tregs based on whether Tregs predominately inhabit secondary lymphoid organs (central Tregs) or tiss...

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Detalles Bibliográficos
Autores principales: Contreras, Amanda, Wiesner, Darin L., Kingstad-Bakke, Brock, Lee, Woojong, Svaren, John P., Klein, Bruce S., Suresh, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410868/
https://www.ncbi.nlm.nih.gov/pubmed/36033397
http://dx.doi.org/10.1155/2022/6789055