FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations

Although both the p53 and forkhead box (FOX) family proteins are key transcription factors associated with cancer progression, their direct relationship is unknown. Here, we found that FOX family proteins bind to the non-canonical homotypic cluster of the p53 promoter region (TP53). Analysis of crys...

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Detalles Bibliográficos
Autores principales: Choi, Yuri, Luo, Yongyang, Lee, Seunghwa, Jin, Hanyong, Yoon, Hye-Jin, Hahn, Yoonsoo, Bae, Jeehyeon, Lee, Hyung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410875/
https://www.ncbi.nlm.nih.gov/pubmed/35920317
http://dx.doi.org/10.1093/nar/gkac673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410875/
https://www.ncbi.nlm.nih.gov/pubmed/35920317
http://dx.doi.org/10.1093/nar/gkac673

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