Modeling splicing outcome by combining 5′ss strength and splicing regulatory elements

Correct pre-mRNA processing in higher eukaryotes vastly depends on splice site recognition. Beyond conserved 5′ss and 3′ss motifs, splicing regulatory elements (SREs) play a pivotal role in this recognition process. Here, we present in silico designed sequences with arbitrary a priori prescribed spl...

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Detalles Bibliográficos
Autores principales: Müller, Lisa, Ptok, Johannes, Nisar, Azlan, Antemann, Jennifer, Grothmann, Ramona, Hillebrand, Frank, Brillen, Anna-Lena, Ritchie, Anastasia, Theiss, Stephan, Schaal, Heiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410876/
https://www.ncbi.nlm.nih.gov/pubmed/35947702
http://dx.doi.org/10.1093/nar/gkac663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410876/
https://www.ncbi.nlm.nih.gov/pubmed/35947702
http://dx.doi.org/10.1093/nar/gkac663

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