TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation

DNA methylation (5-methylcytosine (5mC)) is critical for genome stability and transcriptional regulation in mammals. The discovery that ten-eleven translocation (TET) proteins catalyze the oxidation of 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) revol...

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Detalles Bibliográficos
Autores principales: Stolz, Paul, Mantero, Angelo Salazar, Tvardovskiy, Andrey, Ugur, Enes, Wange, Lucas E, Mulholland, Christopher B, Cheng, Yuying, Wierer, Michael, Enard, Wolfgang, Schneider, Robert, Bartke, Till, Leonhardt, Heinrich, Elsässer, Simon J, Bultmann, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410877/
https://www.ncbi.nlm.nih.gov/pubmed/35904814
http://dx.doi.org/10.1093/nar/gkac642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410877/
https://www.ncbi.nlm.nih.gov/pubmed/35904814
http://dx.doi.org/10.1093/nar/gkac642

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